CLDN8

Claudin-8 is a protein that in humans is encoded by the CLDN8 gene.^[5][6] It belongs to the group of claudins.

CLDN8
Identifiers
Aliases	CLDN8, HEL-S-79, claudin 8
External IDs	OMIM: 611231; MGI: 1859286; HomoloGene: 8117; GeneCards: CLDN8; OMA:CLDN8 - orthologs
Gene location (Human) Chr. Chromosome 21 (human)[1] Band 21q22.11 Start 30,214,006 bp[1] End 30,216,097 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 C3.3 Start 88,357,716 bp[2] End 88,360,071 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of sigmoid colon kidney tubule parotid gland rectum renal medulla bronchial epithelial cell human kidney hair follicle skin of thigh seminal vesicula Top expressed in seminal vesicula transitional epithelium of urinary bladder vestibular membrane of cochlear duct vestibular sensory epithelium left colon right kidney submandibular gland parotid gland medullary collecting duct stria vascularis More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural molecule activity protein binding identical protein binding Cellular component membrane cell junction basolateral plasma membrane integral component of membrane apicolateral plasma membrane endoplasmic reticulum plasma membrane bicellular tight junction Biological process calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9073 54420 Ensembl ENSG00000156284 ENSMUSG00000050520 UniProt P56748 Q9Z260 RefSeq (mRNA) NM_199328 NM_012132 NM_018778 RefSeq (protein) NP_955360 NP_061248 Location (UCSC) Chr 21: 30.21 – 30.22 Mb Chr 16: 88.36 – 88.36 Mb PubMed search [3] [4]
Wikidata
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