Butaxamine

Butaxamine
Clinical data
Other names	Butoxamine
ATC code	None;
Identifiers
	IUPAC name (1S,2S)-1-(2,5-Dimethoxyphenyl)-2-(tert-butylamino)propan-1-ol;
CAS Number	1937-89-9 ;
PubChem CID	134495;
ChemSpider	118552 ;
UNII	0NM31M53PW;
ChEMBL	ChEMBL289093;
Chemical and physical data
Formula	C15H25NO3
Molar mass	267.369 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@@H]([C@@H](C1=C(C=CC(=C1)OC)OC)O)NC(C)(C)C;
	InChI InChI=1S/C15H25NO3/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6/h7-10,14,16-17H,1-6H3/t10-,14-/m0/s1; Key:TWUSDDMONZULSC-HZMBPMFUSA-N;
	(verify)

Butaxamine (INN; also known as butoxamine) is a β₂-selective beta blocker.^[1]^[2] Its primary use is in experimental situations in which blockade of β₂ receptors is necessary to determine the activity of the drug (i.e. if the β₂ receptor is completely blocked, but the given effect is still present, the given effect is not a characteristic of the β₂ receptor). It has no clinical use. An alternative name is α-(1-[tert-butylamino]ethyl)-2,5-dimethoxybenzyl alcohol.

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[1]
"Definition: butoxamine from Online Medical Dictionary".
[2]
Hillman KL, Doze VA, Porter JE (August 2005). "Functional characterization of the beta-adrenergic receptor subtypes expressed by CA1 pyramidal cells in the rat hippocampus". J. Pharmacol. Exp. Ther. 314 (2): 561–7. doi:10.1124/jpet.105.084947. PMID 15908513. S2CID 12446381.

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[urlDefinition:_butoxamine_from_Online_Medical_Dictionary-1] [1]
"Definition: butoxamine from Online Medical Dictionary".

[pmid15908513-2] [2]
Hillman KL, Doze VA, Porter JE (August 2005). "Functional characterization of the beta-adrenergic receptor subtypes expressed by CA1 pyramidal cells in the rat hippocampus". J. Pharmacol. Exp. Ther. 314 (2): 561–7. doi:10.1124/jpet.105.084947. PMID 15908513. S2CID 12446381.

[1]

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Butaxamine

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