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Botryoid odontogenic cyst (BOC) is a type of developmental odontogenic cyst that is extremely rare.[1] It is thought to be a lateral periodontal cyst (LPC) variant with a higher risk of recurrence.[2] Weathers and Waldron coined the term BOC in 1973.[3] Adults over the age of 50 are the most affected.[4] BOC appears as a slow-growing lesion that is symptomatic in approximately 70% of cases.[5]
BOC patients frequently complain of swelling, as well as pain and paraesthesia. BOCs are larger cysts that range in size from 4 mm to 45 mm and can be unilocular or multilocular.[1]
The BOC has a thin epithelial cyst lining composed of flattened squamous or cuboidal cells with focal plaque-like thickenings under the microscope. Clear cells may be seen in the cyst lining or among the epithelial rests dispersed among the fibrous connective-tissue wall on rare occasions.[6]
In terms of appearance, BOC shares similarities with some odontogenic tumors such as ameloblastoma, odontogenic myxoma, adenomatoid odontogenic tumor, and others. Incisional biopsy can be used to perform preoperative differential diagnosis.[6]
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