Blue toe syndrome

Blue toe syndrome is a situation that may reflect atherothrombotic (clots resulting from the build-up of fats, cholesterol, and other substances in and on the artery walls)^[1] microembolism, causing transient focal ischaemia, a temporary blockage of blood flow to the brain or spinal cord,^[2] occasionally with minor apparent tissue loss, but without diffuse forefoot ischemia.^[3] The development of blue or violaceous toes can also occur with trauma, cold-induced injury, disorders producing generalized cyanosis, decreased arterial flow, impaired venous outflow, and abnormal circulating blood.^[4][5][6][7] The terms "blue toe syndrome", "grey toe syndrome" and "purple toe syndrome" are sometimes used interchangeably.^[8]

Blue toe syndrome
Specialty	Cardiology

Studies may include echocardiography, thoracic and abdominal CT or MRI,^{[9][10][11][12]} peripheral arterial run off imaging studies, hypercoagulopathy labs, and interrogation of syndromes that lead to peripheral vascular pathology.^[13]

See also

• Warfarin § Purple toe syndrome
• Cholesterol embolism