BAIAP2L1

Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 is a protein that in humans is encoded by the BAIAP2L1 gene.^[5]

BAIAP2L1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2KXC, 2LNH
Identifiers
Aliases	BAIAP2L1, IRTKS, BAI1 associated protein 2 like 1, BAR/IMD domain containing adaptor protein 2 like 1
External IDs	OMIM: 611877; MGI: 1914148; HomoloGene: 23123; GeneCards: BAIAP2L1; OMA:BAIAP2L1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q21.3-q22.1 Start 98,291,650 bp[1] End 98,401,090 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 144,201,336 bp[2] End 144,294,922 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell secondary oocyte tendon of biceps brachii amniotic fluid cartilage tissue bronchial epithelial cell duodenum mucosa of ileum mucosa of transverse colon olfactory zone of nasal mucosa Top expressed in secondary oocyte primary oocyte zygote right lung lobe left colon lumbar spinal ganglion epithelium of stomach pyloric antrum mucous cell of stomach otic placode More reference expression data BioGPS More reference expression data
Gene ontology Molecular function actin binding proline-rich region binding protein binding cadherin binding involved in cell-cell adhesion Cellular component cytosol plasma membrane extracellular exosome cytoskeleton nucleoplasm actin cytoskeleton cytoplasm Biological process insulin receptor signaling pathway regulation of actin filament polymerization plasma membrane organization positive regulation of actin cytoskeleton reorganization positive regulation of actin filament polymerization response to bacterium regulation of insulin receptor signaling pathway actin filament bundle assembly actin crosslink formation cell-cell adhesion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55971 66898 Ensembl ENSG00000006453 ENSMUSG00000038859 UniProt Q9UHR4 Q9DBJ3 RefSeq (mRNA) NM_018842 NM_025833 RefSeq (protein) NP_061330 NP_080109 Location (UCSC) Chr 7: 98.29 – 98.4 Mb Chr 5: 144.2 – 144.29 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000006453 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000038859 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: BAIAP2L1 BAI1-associated protein 2-like 1".

Further reading

• Millard TH, Dawson J, Machesky LM (2007). "Characterisation of IRTKS, a novel IRSp53/MIM family actin regulator with distinct filament bundling properties". J. Cell Sci. 120 (Pt 9): 1663–72. doi:10.1242/jcs.001776. PMID 17430976. S2CID 39973979.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
• Sanger Centre T, Washington University Genome Sequencing Cente T (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.

External links

• Human BAIAP2L1 genome location and BAIAP2L1 gene details page in the UCSC Genome Browser.