BAAT

Bile acid-CoA:amino acid N-acyltransferase is an enzyme that in humans is encoded by the BAAT gene.^[5]

BAAT
Identifiers
Aliases	BAAT, BACAT, BAT, bile acid-CoA:amino acid N-acyltransferase, BACD1, HCHO
External IDs	OMIM: 602938; MGI: 106642; HomoloGene: 1286; GeneCards: BAAT; OMA:BAAT - orthologs
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q31.1 Start 101,354,182 bp[1] End 101,385,400 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4 B1|4 26.51 cM Start 49,489,422 bp[2] End 49,506,557 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in liver right lobe of liver gallbladder islet of Langerhans superior frontal gyrus primary visual cortex gastrocnemius muscle Brodmann area 9 muscle of thigh prefrontal cortex Top expressed in left lobe of liver gallbladder embryo embryo Ileal epithelium lactiferous gland right kidney jejunum thoracic diaphragm yolk sac More reference expression data BioGPS More reference expression data
Gene ontology Molecular function thiolester hydrolase activity very long chain acyl-CoA hydrolase activity signaling receptor binding transferase activity medium-chain acyl-CoA hydrolase activity hydrolase activity N-acyltransferase activity palmitoyl-CoA hydrolase activity long-chain acyl-CoA hydrolase activity carboxylic ester hydrolase activity glycine N-choloyltransferase activity protein binding acyltransferase activity myristoyl-CoA hydrolase activity acyl-CoA hydrolase activity Cellular component cytoplasm peroxisome peroxisomal matrix cytosol Biological process bile acid conjugation liver development lipid metabolism animal organ regeneration acyl-CoA metabolic process taurine metabolic process bile acid metabolic process glycine metabolic process bile acid biosynthetic process fatty acid metabolic process protein targeting to peroxisome Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 570 12012 Ensembl ENSG00000136881 ENSG00000276559 ENSMUSG00000039653 UniProt Q14032 Q91X34 RefSeq (mRNA) NM_001701 NM_001127610 NM_001374715 NM_007519 RefSeq (protein) NP_001121082 NP_001692 NP_001361644 NP_031545 Location (UCSC) Chr 9: 101.35 – 101.39 Mb Chr 4: 49.49 – 49.51 Mb PubMed search [3] [4]
Wikidata
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The protein encoded by this gene is a liver enzyme that catalyzes the transfer of the bile acid moiety from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates which serve as detergents in the gastrointestinal tract.^[5]