Avizafone

Diazepam prodrug From Wikipedia, the free encyclopedia

Avizafone

Avizafone[1] (Pro-Diazepam) is a water-soluble prodrug of the benzodiazepine derivative diazepam. It can be administered intramuscularly.

Quick Facts Clinical data, Routes ofadministration ...
Avizafone
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Clinical data
Routes of
administration
Intramuscular injection
ATC code
  • none
Identifiers
  • (2S)-2,6-diamino-N-{[(2-benzoyl-4-chlorophenyl)methylcarbamoyl]methyl}hexanamide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H27ClN4O3
Molar mass430.93 g·mol−1
3D model (JSmol)
  • Clc1cc(c(N(C(=O)CNC(=O)[C@@H](N)CCCCN)C)cc1)C(=O)c2ccccc2
  • InChI=1S/C22H27ClN4O3/c1-27(20(28)14-26-22(30)18(25)9-5-6-12-24)19-11-10-16(23)13-17(19)21(29)15-7-3-2-4-8-15/h2-4,7-8,10-11,13,18H,5-6,9,12,14,24-25H2,1H3,(H,26,30)/t18-/m0/s1 Y
  • Key:LTKOVYBBGBGKTA-SFHVURJKSA-N Y
 NY (what is this?)  (verify)
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Avizafone is metabolised by enzymes in the blood to form the active drug diazepam. It is used mainly as an antidote to poisoning with organophosphate nerve agents.[2][3][4]

See also

References

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