Aaptos aaptos

Aaptos aaptos is a species of sea sponge belonging to the family Suberitidae, first described in 1864 by.^[1][2]

Aaptos aaptos
Scientific classification
Domain:	Eukaryota
Kingdom:	Animalia
Phylum:	Porifera
Class:	Demospongiae
Order:	Suberitida
Family:	Suberitidae
Genus:	Aaptos aaptos (Schmidt, 1864)[1]
Synonyms
List Aaptos adriatica Gray, 1867 Ancorina aaptos Schmidt, 1864 Ancorina adriatica sensu Van Soest, 2002 [lapsus] Suberites aaptus (Schmidt, 1864) Suberites spissus Topsent, 1892 Tuberella aaptos (Schmidt, 1864) Tuberella tethyoides Keller, 1880

This particular species is known to contain adrenoceptor-blocking compounds.^[3] While it is highly toxic to fish, it is known to be preyed upon by the hawksbill turtle, Eretmochelys imbricata.^[4]

The methanol extract of Aaptos aaptos has been found to reduce the antioxidants in cancer cells, which increases oxidative stress selectively in cells which contributes to their antiproliferative effects.^[5]

Aaptamine, an alkaloid isolated from Aaptos aaptos^[3]

References

1. World Register of Marine Species Retrieved August 25, 2012
2. Schmidt, E.O. (1864) Supplement der Spongien des adriatischen Meeres. Enthaltend die Histiologie und systematische Ergänzungen. Leipzig : Engelmann 48 pp. 4 pls. [33].
3. Nakamura, Hideshi; Kobayashi, Jun'ichi; Ohizumi, Yasushi; Hirata, Yoshimasa (1982). "Isolation and structure of aaptamine a novel heteroaromatic substance possessing α-blocking activity from the sea sponge Aaptos aaptos". Tetrahedron Letters. 23 (52): 5555–5558. doi:10.1016/S0040-4039(00)85893-1. ISSN 0040-4039.
4. Meylan, Anne (1988-01-12). "Spongivory in Hawksbill Turtles: A Diet of Glass". Science. 239 (4838). American Association for the Advancement of Science: 393–395. doi:10.1126/science.239.4838.393. JSTOR 1700236. PMID 17836872.
5. Shiau, Jun-Ping; Lee, Min-Yu; Tang, Jen-Yang; Huang, Hsin; Lin, Zheng-Yu; Su, Jui-Hsin; Hou, Ming-Feng; Cheng, Yuan-Bin; Chang, Hsueh-Wei (2022-12-16) [Published December 16, 2022]. "Marine Sponge Aaptos suberitoides Extract Improves Antiproliferation and Apoptosis of Breast Cancer Cells without Cytotoxicity to Normal Cells In Vitro". Pharmaceuticals: 19 – via MDPI.{{cite journal}}: CS1 maint: year (link)