ATP9A

Probable phospholipid-transporting ATPase IIA is a protein that in humans is encoded by the ATP9A gene.^[5][6]

ATP9A
Identifiers
Aliases	ATP9A, ATPIIA, ATPase phospholipid transporting 9A (putative)
External IDs	OMIM: 609126; MGI: 1330826; HomoloGene: 69194; GeneCards: ATP9A; OMA:ATP9A - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q13.2 Start 51,596,514 bp[1] End 51,768,390 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 H3 Start 168,476,358 bp[2] End 168,584,329 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus Brodmann area 46 Brodmann area 23 orbitofrontal cortex internal globus pallidus entorhinal cortex superior frontal gyrus postcentral gyrus paraflocculus of cerebellum Brodmann area 10 Top expressed in perirhinal cortex entorhinal cortex CA3 field primary visual cortex dentate gyrus of hippocampal formation granule cell superior frontal gyrus cerebellar cortex central gray substance of midbrain nucleus of stria terminalis dorsomedial hypothalamic nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function ATPase-coupled intramembrane lipid transporter activity nucleotide binding ATP binding magnesium ion binding hydrolase activity metal ion binding Cellular component perinuclear region of cytoplasm integral component of membrane recycling endosome endosome trans-Golgi network plasma membrane Golgi apparatus early endosome early endosome membrane membrane Biological process phospholipid transport endocytosis retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum phospholipid translocation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10079 11981 Ensembl ENSG00000054793 ENSMUSG00000027546 UniProt O75110 O70228 RefSeq (mRNA) NM_006045 NM_001289445 NM_001289446 NM_015731 NM_001354977 NM_001354978 RefSeq (protein) NP_006036 NP_001276374 NP_001276375 NP_056546 NP_001341906 NP_001341907 Location (UCSC) Chr 20: 51.6 – 51.77 Mb Chr 2: 168.48 – 168.58 Mb PubMed search [3] [4]
Wikidata
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References

1. GRCh38: Ensembl release 89: ENSG00000054793 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027546 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "ATP9A - Probable phospholipid-transporting ATPase IIA - Homo sapiens (Human) - ATP9A gene & protein". www.uniprot.org. Retrieved 9 April 2022.
6. "Entrez Gene: ATPase phospholipid transporting 9A (putative)". Retrieved 2016-10-04.

Further reading

• Uhl GR, Liu QR, Drgon T, Johnson C, Walther D, Rose JE, David SP, Niaura R, Lerman C (2008). "Molecular genetics of successful smoking cessation: convergent genome-wide association study results". Arch. Gen. Psychiatry. 65 (6): 683–93. doi:10.1001/archpsyc.65.6.683. PMC 2430596. PMID 18519826.
• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.