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Chemical compound From Wikipedia, the free encyclopedia
1-Amino-1,3-dicarboxycyclopentane (ACPD) is a chemical compound that binds to the metabotropic glutamate receptor (mGluR),[2] acting as a mGluR agonist. ACPD is a rigid analogue of the neurotransmitter glutamate and does not activate ionotropic glutamate receptors.[3] However, it has been reported to be an agonist of the glycine site of the NMDA receptor.[citation needed] ACPD can induce convulsions in neonatal rats.[4]
Names | |
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Preferred IUPAC name
1-Aminocyclopentane-1,3-dicarboxylic acid[1] | |
Identifiers | |
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3D model (JSmol) |
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Abbreviations | ACPD |
ChEMBL | |
ChemSpider | |
MeSH | 1-amino-1,3-dicarboxycyclopentane |
PubChem CID |
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RTECS number |
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CompTox Dashboard (EPA) |
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Properties | |
C7H11NO4 | |
Molar mass | 173.168 g·mol−1 |
Appearance | White crystals |
20 g dm−3 | |
Solubility in ethanol | 240 mg dm−3 |
log P | -0.709 |
Acidity (pKa) | 2.112 |
Basicity (pKb) | 11.885 |
Isoelectric point | 2.84 |
Hazards | |
GHS labelling: | |
Warning | |
H302, H312, H315, H319, H332, H335 | |
P261, P280, P305+P351+P338 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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