4-Aminoquinoline

4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline. The compound has been used as a precursor for the synthesis of its derivatives.^[1]

4-Aminoquinoline

Names
Preferred IUPAC name Quinolin-4-amine
Identifiers
CAS Number	578-68-7 N
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL58146 Y
ChemSpider	61751 Y
ECHA InfoCard	100.167.771
PubChem CID	68476
UNII	GTE5P5L97N Y
CompTox Dashboard (EPA)	DTXSID70206491
InChI InChI=1S/C9H8N2/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H,(H2,10,11) Y Key: FQYRLEXKXQRZDH-UHFFFAOYSA-N Y
SMILES n1ccc(c2ccccc12)N
Properties
Chemical formula	C9H8N2
Molar mass	144.177 g·mol−1
Appearance	Powder to crystalline, White/Yellow/Orange
Melting point	151–155 °C (304–311 °F; 424–428 K)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	Causes skin and serious eye irritation
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

See also: 8-Aminoquinoline

A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections.^[2] Examples include amodiaquine, chloroquine, and hydroxychloroquine.^[3] Other uses for the derivatives are: anti-asthmatic, antibacterial, anti-fungal, anti-malarial, antiviral and anti-inflammatory agents.^[1]

A patent application for 4-aminoquinoline compounds was filed in 2002 and published in 2005.^[4]

• 
  Amodiaquine
• 
  Chloroquine
• 
  Hydroxychloroquine

See also

• Quinoline
• 8-Hydroxyquinoline
• Ionophore