The 2020 All-Big 12 Conference football team consists of American football players chosen as All-Big 12 Conference players for the 2020 Big 12 Conference football season. The conference recognizes two official All-Big 12 selectors: (1) the Big 12 conference coaches selected separate offensive and defensive units and named first- and second-team players (the "Coaches" team); and (2) a panel of sports writers and broadcasters covering the Big 12 also selected offensive and defensive units and named first- and second-team players (the "Media" team).
Centers
- Creed Humphrey, Oklahoma (Coaches-1; Media-1)
- Colin Newell, Iowa State (Coaches-1; Media-2)
Guards
- Jack Anderson, Texas Tech (Coaches-1; Media-1)
- Michael Brown, West Virginia (Coaches-2; Media-2)
- Derek Schweiger, Iowa State (Coaches-2; Media-2)
- Josh Sills, Oklahoma State (Media-1)
Defensive linemen
- JaQuan Bailey, Iowa State (Coaches-1; Media-1)
- Wyatt Hubert, Kansas State (Coaches-1; Media-1)
- Darius Stills, West Virginia (Coaches-1; Media-1)
- Ochaun Mathis, TCU (Coaches-2; Media-2)
- Akheem Mesidor, West Virginia (Coaches-2)
- Will McDonald IV, Iowa State (Coaches-1; Media-2)
- Joseph Ossai, Texas (Coaches-1; Media-2)
- Ronnie Perkins, Oklahoma (Coaches-2)
- Dante Stills, West Virginia (Media-2)
- Isaiah Thomas, Oklahoma (Coaches-2; Media-1)
- Drew Wiley, Kansas State (Media-2)
- Perrion Winfrey, Oklahoma (Coaches-2)
Defensive backs
- Tre Tomlinson, TCU (Coaches-1; Media-1)
- Trevon Moehrig, TCU (Coaches-1; Media-1)
- Jalen Pitre, Baylor (Coaches-1; Media-1)
- Zech McPhearson, Texas Tech (Coaches-1; Media-1)
- Greg Eisworth, Iowa State (Coaches-1; Media-2)
- Tre Brown, Oklahoma (Coaches-2; Media-2)
- Rodarius Williams, Oklahoma State (Coaches-2; Media-2)
- Alonzo Addae, West Virginia (Coaches-2)
- Chris Brown, Texas (Coaches-2)
- Kolby Harvell-Peel, Oklahoma State (Coaches-2)
- Tykee Smith, West Virginia (Media-2)
Kickers
- Gabe Brkic, Oklahoma (Coaches-1; Media-1)
- Cameron Dicker, Texas (Coaches-2; Media-2)
Punters
- Austin McNamara, Texas Tech (Coaches-1; Media-1)
- Jordy Sandy, TCU (Coaches-2; Media-2)
All-purpose / Return specialists
Bold = selected as a first-team player by both the coaches and media panel
Coaches = selected by Big 12 Conference coaches[1]
Media = selected by a media panel[2]