The following lists events that happened during 2002 in South Africa.
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- January
- 29 – Doctors Without Borders, an international humanitarian organisation, begins importing a cheap generic version of patented AIDS drugs into South Africa in defiance of South Africa's patent laws.
February
- 9 – Bulelani Vukwana, an off-duty security guard, kills ten people and wounds others during a shooting spree in Mdantsane, near East London. The massacre - triggered by a failed relationship - ends when Vukwana kills himself, surrounded by police.[2]
- March
- 27 – Health Minister Manto Tshabalala-Msimang approaches the Constitutional Court to stop the issuing of Nevirapine.
- Sivan Pillay, Ed Jordan, Nkhensani Mangani and Karl Anderson are appointed as the first judges of reality show Coca-Cola Popstars, which yields two new pop groups, winners 101 and runners-up Afro Z.
- April
- May
- June
- 16 – The Hector Pieterson Museum becomes the first museum to open in Soweto.
- 27 – Two South African Air Force Oryx helicopters, flying from the South African Antarctic research ship Agulhas, takes emergency food supplies and evacuates 21 Russian scientists from the German-owned Magdalena Oldendorff which has been trapped in ice off Antarctica since 16 June.
- July
- 15 – Nelson Mandela calls on government and business leaders worldwide to find ways to provide access to treatment to people living with HIV/AIDS.
- August
- 8 – The government announces the approval of an anti-retroviral roll-out plan.
- 9 – Ed Fagan leads a $50bn class action suit by a few apartheid-era victims against international firms and banks who profited from dealings with the apartheid government.
- 25 – The Medicines Control Council threatens to de-register Nevirapine unless further studies and appropriate documentation can show its efficacy in the prevention of mother-to-child transmission of HIV.
- September
- October
- November
- December
- Unknown date