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Chemical compound From Wikipedia, the free encyclopedia
1,8-Naphthyridine is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric naphthyridines, a subset of diazanaphthalenes with nitrogen in the separate rings.[2][3] Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.[4]
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Names | |
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Preferred IUPAC name
1,8-Naphthyridine[1] | |
Identifiers | |
3D model (JSmol) |
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109347 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.201.052 |
EC Number |
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27124 | |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C8H6N2 | |
Molar mass | 130.150 g·mol−1 |
Appearance | yellow solid |
Density | 1.359 g/cm3 |
Melting point | 98–99 °C (208–210 °F; 371–372 K) |
Hazards | |
GHS labelling: | |
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Warning | |
H315, H319, H335 | |
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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With flanking nitrogen centers, 1,8-naphthyridine serves as a binucleating ligand in coordination chemistry.[5][6]
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