ZNF655

Zinc finger protein 655 is a protein that in humans is encoded by the ZNF655 gene.^[5][6][7]

ZNF655
Identifiers
Aliases	ZNF655, VIK, VIK-1, zinc finger protein 655
External IDs	OMIM: 617891; MGI: 1919861; HomoloGene: 12473; GeneCards: ZNF655; OMA:ZNF655 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q22.1 Start 99,558,406 bp[1] End 99,576,453 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 G2 Start 145,168,525 bp[2] End 145,184,112 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of ileum epithelium of colon skin of arm skin of thigh body of pancreas gastric mucosa cardiac muscle tissue of right atrium thymus cartilage tissue muscle layer of sigmoid colon Top expressed in secondary oocyte zygote primary oocyte otolith organ hand cumulus cell utricle medullary collecting duct substantia nigra medial ganglionic eminence More reference expression data BioGPS n/a
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding protein binding metal ion binding nucleic acid binding molecular function DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoplasm nucleolus nucleus Biological process negative regulation of G1/S transition of mitotic cell cycle regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79027 72611 Ensembl ENSG00000197343 ENSMUSG00000007812 UniProt Q8N720 n/a RefSeq (mRNA) NM_138494 NM_001009956 NM_001009957 NM_001009958 NM_001009960 NM_001083956 NM_001085366 NM_001085367 NM_001085368 NM_024061 NM_001363332 NM_001363333 NM_001363334 NM_001083958 NM_028298 NM_001347533 NM_001363449 NM_001363451 NM_001363452 RefSeq (protein) NP_001009958 NP_001009960 NP_001077425 NP_001078835 NP_001078836 NP_001078837 NP_076966 NP_612503 NP_001350261 NP_001350262 NP_001350263 n/a Location (UCSC) Chr 7: 99.56 – 99.58 Mb Chr 5: 145.17 – 145.18 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

This gene encodes a zinc finger protein. The zinc finger proteins are involved in DNA binding and protein–protein interactions. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.^[7]

References

1. GRCh38: Ensembl release 89: ENSG00000197343 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000007812 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Laity JH, Lee BM, Wright PE (Feb 2001). "Zinc finger proteins: new insights into structural and functional diversity". Curr Opin Struct Biol. 11 (1): 39–46. doi:10.1016/S0959-440X(00)00167-6. PMID 11179890.
6. Houlard M, Romero-Portillo F, Germani A, Depaux A, Regnier-Ricard F, Gisselbrecht S, Varin-Blank N (Jan 2005). "Characterization of VIK-1: a new Vav-interacting Kruppel-like protein". Oncogene. 24 (1): 28–38. doi:10.1038/sj.onc.1208043. PMID 15558030. S2CID 29942892.
7. "Entrez Gene: ZNF655 zinc finger protein 655".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
• Thompson EE, Kuttab-Boulos H, Yang L, et al. (2006). "Sequence diversity and haplotype structure at the human CYP3A cluster". Pharmacogenomics J. 6 (2): 105–14. doi:10.1038/sj.tpj.6500347. PMID 16314882. S2CID 10102745.
• Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.

External links

• ZNF655+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.