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Veratridine
Steroidal alkaloid found in plants of the lily family / From Wikipedia, the free encyclopedia
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Veratridine is a steroidal alkaloid found in plants of the lily family, specifically the genera Veratrum and Schoenocaulon.[1] Upon absorption through the skin or mucous membranes, it acts as a neurotoxin by binding to and preventing the inactivation of voltage-gated sodium ion channels in heart, nerve, and skeletal muscle cell membranes.[2] Veratridine increases nerve excitability and intracellular Ca2+ concentrations.
Quick Facts Names, Identifiers ...
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Names | |
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IUPAC name
4β,12,14,16β,17,20-Hexahydroxy-4α,9-epoxycevan-3β-yl 3,4-dimethoxybenzoate | |
Systematic IUPAC name
(3S,4S,4aS,6aS,6bR,8S,8aS,9R,9aS,12S,15aS,15bR,16aR,16bS)-4,6b,8,8a,9,15b-Hexahydroxy-9,12,16b-trimethyldocosahydro-2H-4,16a-epoxybenzo[4,5]indeno[1,2-h]pyrido[1,2-b]isoquinolin-3-yl 3,4-dimethoxybenzoate | |
Other names
(3β,4β,16β)-4,12,14,16,17,20-Hexahydroxy-4,9-epoxycevan-3yl 3,4-dimethoxybenzoate 3-Veratroylveracevine | |
Identifiers | |
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3D model (JSmol) |
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ChEMBL | |
ChemSpider |
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ECHA InfoCard | 100.000.690 ![]() |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C36H51NO11 | |
Molar mass | 673.800 g·mol−1 |
Melting point | 160 to 180 °C (320 to 356 °F; 433 to 453 K) |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards |
Toxic |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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