Vamorolone
Chemical compound / From Wikipedia, the free encyclopedia
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Vamorolone, sold under the brand name Agamree, is a synthetic corticosteroid, which is used for the treatment of Duchenne muscular dystrophy.[4][5][6][7][8] It is taken by mouth.[1] It is a dual atypical glucocorticoid and antimineralocorticoid.[9]
Quick Facts Clinical data, Trade names ...
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Trade names | Agamree |
Other names | VBP; VBP-15; 17α,21-Dihydroxy-16α-methylpregna-1,4,9(11)-triene-3,20-dione |
AHFS/Drugs.com | Monograph |
MedlinePlus | a624005 |
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Routes of administration | By mouth |
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ECHA InfoCard | 100.032.874 |
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Formula | C22H28O4 |
Molar mass | 356.462 g·mol−1 |
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The most common adverse reactions include cushingoid features, psychiatric disorders, vomiting, increasted weight, and vitamin D deficiency.[10]
Vamorolone was approved for medical use in the United States in October 2023,[11][10] and in the European Union in December 2023.[2][3]