User:Waffeln/sandbox
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O-linked glycosylation is the attachment of a sugar molecule to the oxygen atom of either serine (Ser) or threonine (Thr) amino acids in a protein destined for secretion from the cell. O-glycosylation is studied in biochemistry, and occurs in the Golgi apparatus after the protein has been produced, as a post-translational modification [1]. Several different sugars can be added to the amino acid residues, and affect the protein in different ways by changing protein stability and regulating protein activity. O-glycans have numerous functions throughout the body, including trafficking of cells in the immune system, allowing recognition of foreign organs, controlling cell metabolism and providing cartilage and tendon flexibility [2]. Because of this variety of functions, changes in O-glycosylation are important in many diseases including cancer, diabetes and Alzheimer's. O-glycosylation occurs in eukaryotes, archaea and a number of pathogenic bacteria including Burkholderia cenocepacia [3], Neisseria gonorrhoeae [4] and Acinetobacter baumannii [5].
This is the user sandbox of Waffeln. A user sandbox is a subpage of the user's user page. It serves as a testing spot and page development space for the user and is not an encyclopedia article. Create or edit your own sandbox here. Other sandboxes: Main sandbox | Template sandbox Finished writing a draft article? Are you ready to request review of it by an experienced editor for possible inclusion in Wikipedia? Submit your draft for review! |