User:Mr. Ibrahem/Tecovirimat
From Wikipedia, the free encyclopedia
Tecovirimat, sold under the brand name Tpoxx, is an antiviral medication with activity against smallpox.[2] Other uses may include monkeypox, cowpox, and complications of smallpox vaccination.[3] It is taken by mouth.[2]
Quick Facts Clinical data, Trade names ...
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Clinical data | |
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Trade names | Tpoxx |
Other names | ST-246 |
AHFS/Drugs.com | Monograph |
Routes of administration | By mouth |
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Chemical and physical data | |
Formula | C19H15F3N2O3 |
Molar mass | 376.335 g·mol−1 |
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Common side effects include nausea, headache, and abdominal pain.[2] No serious side effects have been seen.[4] It works by blocking orthopoxvirus VP37 protein, which prevents the virus from leave a cell.[2]
Tecovirimat became the first drug approved for use in smallpox in the United States in 2018.[5] Two million doses are in the US Strategic National Stockpile in the event that smallpox reoccurs.[6] As of 2021 it is not approved in Europe.[3]