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Tranexamic acid or TXA is used to treat or prevent excessive blood loss during surgery and in various medical conditions or disorders including hemophilia and heavy menstrual bleeding[1]. Side effects are rare (<10%) and include gastrointestinal effects, dizziness, fatigue, headache, and hypersensitivity reactions [2]. Use of tranexamic acid has a potential risk of thrombosis[3].Care should be used in those with kidney disease and high risk of blood clots[1].Tranexamic is safe to use in pregnant women. However, caution should be used in lactating women[1]. It comes in oral and intravenous forms [1]. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.[4]
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Pronunciation | \ˌtran-eks-ˌam-ik-\ |
AHFS/Drugs.com | Consumer Drug Information |
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Routes of administration | Injection and oral |
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Bioavailability | 34% |
Elimination half-life | 3.1 h |
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Formula | C8H15NO2 |
Molar mass | 157.21 g/mol g·mol−1 |
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