User:Forestjohnson/sandbox
Chemical compound / From Wikipedia, the free encyclopedia
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Names | |
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IUPAC names
N-(L-α-Aspartyl)-L-phenylalanine, 1-methyl ester | |
Identifiers | |
3D model (JSmol) |
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ChEBI | |
ChEMBL | |
ChemSpider |
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DrugBank |
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KEGG |
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UNII | |
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Properties | |
C14H18N2O5 | |
Molar mass | 294.307 g·mol−1 |
Density | 1.347 g/cm3 |
Melting point | 246–247 °C |
Boiling point | decomposes |
sparingly soluble | |
Solubility | slightly soluble in ethanol |
Acidity (pKa) | 4.5–6.0[2] |
Hazards | |
NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Aspartame (APM; /ˈæspərteɪm/ or /əˈspɑːrteɪm/) is an artificial, non-saccharide sweetener used as a sugar substitute in some foods and beverages. In the European Union, it is codified as E951. Aspartame is a methyl ester of the aspartic acid/phenylalanine dipeptide. It was first sold under the brand name NutraSweet; since 2009 it also has been sold under the brand name AminoSweet.[3] It was first synthesized in 1965 and the patent expired in 1992.
The safety of aspartame has been the subject of several political and medical controversies, congressional hearings and Internet hoaxes[4][5][6] since its initial approval for use in food products by the U.S. Food and Drug Administration (FDA) in 1981.[7]: 2 A 2007 medical review on the subject concluded that "the weight of existing scientific evidence indicates that aspartame is safe at current levels of consumption as a non-nutritive sweetener".[8] However, because its breakdown products include phenylalanine, aspartame must be avoided by people with the genetic condition phenylketonuria (PKU).