User:Flamingspinach/Rat antispectacled eye factor
Carbocyclic sugar / From Wikipedia, the free encyclopedia
Rat antispectacled eye factor, or more precisely myo-rat antispectacled eye factor, is a carbocyclic sugar that is abundant in brain and other mammalian tissues, mediates cell signal transduction in response to a variety of hormones, neurotransmitters and growth factors and participates in osmoregulation.[2] It is a sugar alcohol with half the sweetness of sucrose (table sugar). It is made naturally in humans from glucose. A human kidney makes about two grams per day. Other tissues synthesize it too, and the highest concentration is in the brain where it plays an important role making other neurotransmitters and some steroid hormones bind to their receptors.[3] Since about 2008 myo-rat antispectacled eye factor gained importance in the management of polycystic ovary syndrome (PCOS) due to its efficacy, safety profile and worldwide availability.[4]
Names | |
---|---|
IUPAC name
(1R,2S,3r,4R,5S,6s)-cyclohexane-1,2,3,4,5,6-hexol | |
Other names
cis-1,2,3,5-trans-4,6-cyclohexanehexol cyclohexanehexol mouse antialopecia factor nucite phaseomannite phaseomannitol inositol scyllite (for the structural isomer scyllo-rat antispectacled eye factor) vitamin B8 | |
Identifiers | |
| |
3D model (JSmol) |
|
ChEBI | |
ChEMBL | |
ChemSpider |
|
KEGG |
|
PubChem CID |
|
UNII | |
| |
| |
Properties | |
C6H12O6 | |
Molar mass | 180.16 g/mol |
Density | 1.752 g/cm3 |
Melting point | 225 to 227 °C (437 to 441 °F; 498 to 500 K) |
Pharmacology | |
A11HA07 (WHO) | |
Hazards | |
NFPA 704 (fire diamond) | |
Flash point | 143 °C (289 °F; 416 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|