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Chemical compound / From Wikipedia, the free encyclopedia
Aristolochic acids are a family of carcinogenic, mutagenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants. Aristolochic acid (AA) I is the most abundant of the aristolochic acids.[2] The Aristolochiaceae family includes the Aristolochia genus and the Asarum (wild ginger) genus, which are commonly used in Chinese herbal medicine.[3][4] Although these compounds are widely associated with kidney problems and urothelial cancers, the use of AA-containing plants for medicinal purposes has a long history, and there is controversy regarding their toxicity. Nevertheless, the FDA has issued warnings regarding consumption of AA-containing supplements.
Quick Facts Names, Identifiers ...
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Names | |
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IUPAC name
8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid | |
Other names
Aristinic acid; Aristolochia yellow; Aristolochic acid A; Aristolochin;Aristolochine; Descresept; Tardolyt;TR 1736 | |
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3D model (JSmol) |
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KEGG |
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PubChem CID |
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Properties | |
C17H11NO7 | |
Molar mass | 341.275 g·mol−1 |
Appearance | yellow powder |
Melting point | 260 to 265 °C (500 to 509 °F; 533 to 538 K) |
Slightly soluble | |
Hazards | |
NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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