User:Alail3/sandbox
From Wikipedia, the free encyclopedia
Iron-binding proteins are carrier proteins and metalloproteins which play many important roles in various organic processes, including metabolism,[1] the immune response,[2] and delivery pathways for small molecules such as oxygen (when bound to iron in heme).[3] Iron is required by humans and bacteria for enzymes and metabolic pathways to function properly.
Iron-dependent enzymes catalyze a variety of different biochemical reactions and can be divided into three broad classes depending on the structure of their active site: mononuclear iron clusters, Rieske (Fe-S) centers, or heme centers.[4] A well-known family of iron-dependent enzymes include oxygenases that facilitate hydroxyl group addition of one or both atoms from diatomic oxygen. Notable enzymes include tryptophan dioxygenase, ferredoxin, and 2-oxoglutarate dioxygenase (a major enzyme in flavonoid biosynthesis).[5]