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Chemical compound From Wikipedia, the free encyclopedia
Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in glycosyltransferase reactions in metabolism.
Names | |
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IUPAC name
Uridine 5′-(α-D-glucopyranosyl dihydrogen diphosphate) | |
Systematic IUPAC name
O1-{[(2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl} O3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] dihydrogen diphosphate | |
Other names
UDP-glucose | |
Identifiers | |
3D model (JSmol) |
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.004.657 |
MeSH | Uridine+Diphosphate+Glucose |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C15H24N2O17P2 | |
Molar mass | 566.302 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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UDP-glucose is used in nucleotide sugar metabolism as an activated form of glucose, a substrate for enzymes called glucosyltransferases.[1]
UDP-glucose is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid.
UDP-glucose can also be used as a precursor of sucrose, lipopolysaccharides and glycosphingolipids.
UDP-glucose consists of the pyrophosphate group, ribose, glucose, and uracil.
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