Tyrocidine
Chemical compound / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Tyrocidine?
Summarize this article for a 10 year old
Tyrocidine is a mixture of cyclic decapeptides produced by the bacteria Brevibacillus brevis found in soil. It can be composed of 4 different amino acid sequences, giving tyrocidine A–D (See figure 1). Tyrocidine is the major constituent of tyrothricin, which also contains gramicidin.[1] Tyrocidine was the first commercially available antibiotic, but has been found to be toxic toward human blood and reproductive cells. The function of tyrocidine within its host B. brevis is thought to be regulation of sporulation.[2]
Names | |
---|---|
IUPAC name
3-((3S,6R,9S,12S,15S,
18S,21S,24S,27R,32aS) -9-(2-amino-2-oxoethyl)- 21-(3-aminopropyl)- 3,6,27-tribenzyl-15- (4-hydroxybenzyl)-24-isobutyl- 18-isopropyl- 1,4,7,10,13,16,19,22,25,28- decaoxodotriacontahydropyrrolo[1,2-a] [1,4,7,10,13,16,19,22,25,28] decaazacyclotriacontin- 12-yl)propanamide | |
Identifiers | |
3D model (JSmol) |
|
ChEBI |
|
ChEMBL |
|
ChemSpider | |
EC Number |
|
KEGG |
|
PubChem CID |
|
UNII |
|
| |
| |
Properties | |
C66H87N13O13 | |
Molar mass | 1270.47628 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
Tyrocidines A, B, and C are cyclic decapeptides. The biosynthesis of tyrocidine involves three enzymes. Parts of its sequence are identical to gramicidin S.