Trypanocidal agent

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A trypanocidal agent is an antiprotozoal agent that acts upon trypanosome parasites.[1]

Examples include:[2]

Resistance

As of 2008, 17[4] or 18[5] African countries had confirmed resistant parasite populations, and as of 2011 that was up to 21.[5] Multiply resistant populations are an increasing problem in the Adamawa Region of Cameroon[6] and south east Mali.[7] The Gibe River Valley in southwest Ethiopia showed universal resistance (in T. congolense isolated from Boran cattle) between July 1989 and February 1993.[8] This likely indicates a permanent loss of function in this area for the tested trypanocides, diminazene aceturate, isometamidium chloride, and homidium chloride.[8]

See also

References

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