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Triamterene
Chemical compound / From Wikipedia, the free encyclopedia
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"Ademine" redirects here. Not to be confused with adenine.
Triamterene (traded under names such as Dyrenium and Dytac) is a potassium-sparing diuretic often used in combination with thiazide diuretics for the treatment of high blood pressure or swelling. The combination with hydrochlorothiazide, is known as hydrochlorothiazide/triamterene.
This section needs additional citations for verification. (June 2012) |
Quick Facts Clinical data, Trade names ...
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Clinical data | |
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Trade names | Dyrenium, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682337 |
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Routes of administration | By mouth |
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Pharmacokinetic data | |
Bioavailability | 30-70% |
Protein binding | 67% |
Metabolism | hydroxylation to para-hydroxytriamterene |
Elimination half-life | 1-2 hours, active metabolite 3 hours |
Excretion | renal <50%, 21% unchanged |
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ECHA InfoCard | 100.006.278 ![]() |
Chemical and physical data | |
Formula | C12H11N7 |
Molar mass | 253.269 g·mol−1 |
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