![cover image](https://wikiwandv2-19431.kxcdn.com/_next/image?url=https://upload.wikimedia.org/wikipedia/commons/thumb/6/62/Ideogram_human_chromosome_22.svg/640px-Ideogram_human_chromosome_22.svg.png&w=640&q=50)
Translocator protein
Human protein / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Translocator protein?
Summarize this article for a 10 year old
Translocator protein (TSPO) is an 18 kDa protein mainly found on the outer mitochondrial membrane.[5] It was first described as peripheral benzodiazepine receptor (PBR), a secondary binding site for diazepam, but subsequent research has found the receptor to be expressed throughout the body and brain.[6] In humans, the translocator protein is encoded by the TSPO gene.[7][8] It belongs to a family of tryptophan-rich sensory proteins. Regarding intramitochondrial cholesterol transport, TSPO has been proposed to interact with StAR (steroidogenic acute regulatory protein) to transport cholesterol into mitochondria, though evidence is mixed.[9]