Thymidine diphosphate

Thymidine diphosphate (TDP) or deoxythymidine diphosphate (dTDP) (also thymidine pyrophosphate, dTPP) is a nucleotide diphosphate. It is an ester of pyrophosphoric acid with the nucleoside thymidine. dTDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase thymine. Unlike the other deoxyribonucleotides, thymidine diphosphate does not always contain the "deoxy" prefix in its name.^[1]

Thymidine diphosphate

Names
IUPAC name Thymidine 5′-(trihydrogen diphosphate)
Systematic IUPAC name [(2R,3S,5R)-3-Hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)oxolan-2-yl]methyl trihydrogen diphosphate
Identifiers
CAS Number	491-97-4 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:18075 N
ChemSpider	144320
PubChem CID	164628
UNII	QQ3K1P45DF Y
CompTox Dashboard (EPA)	DTXSID801027011
InChI InChI=1S/C10H16N2O11P2/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(22-8)4-21-25(19,20)23-24(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,11,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s1 Key: UJLXYODCHAELLY-XLPZGREQSA-N
SMILES CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)O)O
Properties
Chemical formula	C10H16N2O11P2
Molar mass	402.19
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

See also

• Nucleoside
• Nucleotide
• DNA
• RNA
• Oligonucleotide
• dTDP-glucose

References

1. Coghill, Anne M.; Garson, Lorrin R., eds. (2006). The ACS style guide: effective communication of scientific diphosphates information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.