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Teriparatide
Pharmaceutical drug for treating osteoporosis / From Wikipedia, the free encyclopedia
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Teriparatide, sold under the brand name Forteo, is a form of parathyroid hormone (PTH) consisting of the first (N-terminus) 34 amino acids, which is the bioactive portion of the hormone.[13] It is an effective anabolic (promoting bone formation) agent[15] used in the treatment of some forms of osteoporosis.[13][16] Teriparatide is a recombinant human parathyroid hormone analog (PTH 1-34).[13] It has an identical sequence to the 34 N-terminal amino acids of the 84-amino acid human parathyroid hormone.[13]
Quick Facts Clinical data, Trade names ...
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Clinical data | |
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Trade names | Forteo, Forsteo |
Biosimilars | Bonsity,[1] Kauliv,[2] Livogiva,[3] Osnuvo,[4] Qutavina,[5] Sondelbay,[6] Teribone,[7] |
AHFS/Drugs.com | Monograph |
MedlinePlus | a603018 |
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Routes of administration | Subcutaneous |
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Bioavailability | 95% |
Metabolism | Liver (nonspecific proteolysis) |
Elimination half-life | Subcutaneous: 1 hour |
Excretion | Kidney (metabolites) |
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ECHA InfoCard | 100.168.733 ![]() |
Chemical and physical data | |
Formula | C181H291N55O51S2 |
Molar mass | 4117.77 g·mol−1 |
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