TUBGCP2

Gamma-tubulin complex component 2 is a protein that in humans is encoded by the TUBGCP2 gene.^[5][6] It is part of the gamma-tubulin complex, which is required for microtubule nucleation at the centrosome.

TUBGCP2
Identifiers
Aliases	TUBGCP2, GCP-2, GCP2, Grip103, SPBC97, Spc97p, h103p, hGCP2, hSpc97, tubulin gamma complex associated protein 2, ALP4, SPC97, PAMDDFS
External IDs	OMIM: 617817; MGI: 1921487; HomoloGene: 55980; GeneCards: TUBGCP2; OMA:TUBGCP2 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q26.3 Start 133,278,635 bp[1] End 133,318,823 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F4 Start 139,575,868 bp[2] End 139,616,582 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube olfactory zone of nasal mucosa gonad skin of leg skin of abdomen mucosa of transverse colon anterior pituitary granulocyte right ovary left ovary Top expressed in spermatocyte seminiferous tubule maxillary prominence mandibular prominence spermatid somite efferent ductule Gonadal ridge autopod region hand More reference expression data BioGPS More reference expression data
Gene ontology Molecular function structural constituent of cytoskeleton protein binding microtubule minus-end binding gamma-tubulin binding Cellular component cytoplasm cytosol centrosome spindle pole equatorial microtubule organizing center membrane nucleoplasm microtubule organizing center gamma-tubulin small complex spindle pole body cytoplasmic microtubule cytoskeleton microtubule gamma-tubulin complex Biological process centrosome duplication microtubule nucleation by interphase microtubule organizing center mitotic spindle assembly cytoplasmic microtubule organization microtubule cytoskeleton organization microtubule nucleation meiosis mitotic cell cycle spindle assembly protein-containing complex assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10844 74237 Ensembl ENSG00000130640 ENSMUSG00000025474 UniProt Q9BSJ2 Q921G8 RefSeq (mRNA) NM_001256617 NM_001256618 NM_006659 NM_001286007 NM_001286009 NM_001286011 NM_133755 RefSeq (protein) NP_001243546 NP_001243547 NP_006650 NP_001272936 NP_001272938 NP_001272940 NP_598516 Location (UCSC) Chr 10: 133.28 – 133.32 Mb Chr 7: 139.58 – 139.62 Mb PubMed search [3] [4]
Wikidata
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See also

• Tubulin
• TUBGCP3
• TUBGCP4
• TUBGCP5
• TUBGCP6