TRIM50
Mammalian protein found in Homo sapiens / From Wikipedia, the free encyclopedia
Tripartite motif-containing 50, also known as TRIM50, is a human gene.[1] TRIM50 encodes an E3 ubiquitin ligase.[2] The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The gene is located at 7q11.23, near two homologous genes, TRIM73 and TRIM74. TRIM50 is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23.
Quick Facts Tripartite motif-containing 50, Identifiers ...
Tripartite motif-containing 50 | |||||||
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Identifiers | |||||||
Symbol | TRIM50 | ||||||
Alt. symbols | TRIM50A; FLJ32804; MGC138357; MGC138359 | ||||||
NCBI gene | 135892 | ||||||
HGNC | 19017 | ||||||
RefSeq | NM_178125 | ||||||
UniProt | Q86XT4 | ||||||
Other data | |||||||
Locus | Chr. 7 q11.23 | ||||||
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