TOC1 (gene)
Gene that regulates circadian rhythm in plants / From Wikipedia, the free encyclopedia
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Timing of CAB expression 1 is a protein that in Arabidopsis thaliana is encoded by the TOC1 gene. TOC1 is also known as two-component response regulator-like APRR1.
Timing of CAB Expression 1 | |||||||
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Identifiers | |||||||
Organism | Arabidopsis thaliana | ||||||
Symbol | APRR1 | ||||||
Alt. symbols | TOC1, AtTOC1, MFB13.13, PSEUDO-RESPONSE REGULATOR 1 | ||||||
Entrez | 836259 | ||||||
RefSeq (mRNA) | NM_125531.3 | ||||||
RefSeq (Prot) | NP_200946.1 | ||||||
UniProt | Q9LKL2 | ||||||
Other data | |||||||
Chromosome | 5: 24.69 - 24.7 Mb | ||||||
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toc1 | |
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Gene | |
Number of Exons | 6 |
Number of Introns | 5 |
Size | 3.49 kb |
mRNA | |
size | 2713 bp |
Protein | |
Molecular Weight | 69.2 kDa |
pI | 7.5 |
Amino Acids | 618 |
Location in Arabidopsis | |
Chromosome | 5 |
Distance | 79.0 cM |
Locus Tag | AT5G61380 |
TOC1 was the first plant gene that, when mutated, yielded a circadian phenotype. It codes for the transcription factor TOC1, which affects the period of plants' circadian rhythms: built-in, malleable oscillations that repeat every 24 hours. The gene codes for a transcriptional repressor, TOC1, one of five pseudo-response regulators (PRR) that mediate the period of the circadian clock in plants. The TOC1 protein is involved in the clock's evening loop, which is a repressilator that directly inhibits transcription of morning loop genes LHY and CCA1.[1] Toc1 gene is expressed in most plant structures and cells, and has its locus on chromosome 5.[2]