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THIQ
Chemical compound / From Wikipedia, the free encyclopedia
This article is about the selective MC4 agonist. For the heterocyclic amine, see Tetrahydroisoquinoline.
THIQ is a drug used in scientific research, which is the first non-peptide agonist developed that is selective for the melanocortin receptor subtype MC4.[1][2] In animal studies, THIQ stimulated sexual activity in rats,[3] but with little effect on appetite or inflammation.[4] This supports possible application of MC4 selective agonists for the treatment of sexual dysfunction in humans,[5] although THIQ itself has poor oral bioavailability and a short duration of action so improved analogues will need to be developed.[6]
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Formula | C33H41ClN6O2 |
Molar mass | 589.18 g·mol−1 |
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