Suprofen

Suprofen is a nonsteroidal anti-inflammatory drug (NSAID) developed by Janssen Pharmaceutica^[1] that was marketed as 1% eye drops under the trade name Profenal.

Suprofen

Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of administration	Oral, eye drops
ATC code	M01AE07 (WHO)
Legal status
Legal status	Discontinued
Pharmacokinetic data
Protein binding	20%
Identifiers
IUPAC name (RS)-2-[4-(2-thienylcarbonyl)phenyl]propanoic acid
CAS Number	40828-46-4 Y
PubChem CID	5359
IUPHAR/BPS	7298
DrugBank	DB00870 Y
ChemSpider	5166 N
UNII	988GU2F9PE
KEGG	D00452 Y
ChEBI	CHEBI:9362 N
ChEMBL	ChEMBL956 N
CompTox Dashboard (EPA)	DTXSID5045469
ECHA InfoCard	100.050.071
Chemical and physical data
Formula	C14H12O3S
Molar mass	260.31 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(c1ccc(cc1)C(C(=O)O)C)c2sccc2
InChI InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17) N Key:MDKGKXOCJGEUJW-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Uses

Suprofen was originally used as tablet, but oral uses have been discontinued due to renal effects.^[2] It was subsequently used exclusively as a topical ophthalmic solution, typically to prevent miosis during and after ophthalmic surgery.^[3] This application has been discontinued as well, at least in the US.^[4]