Subacute combined degeneration of spinal cord
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Subacute combined degeneration of spinal cord, also known as myelosis funiculus, or funicular myelosis,[1] also Lichtheim's disease,[2][3] and Putnam-Dana syndrome,[4] refers to degeneration of the posterior and lateral columns of the spinal cord as a result of vitamin B12 deficiency (most common). It may also occur similarly as result of vitamin E deficiency,[5] and copper deficiency.[6] It is usually associated with pernicious anemia.
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Subacute combined degeneration of spinal cord | |
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Diagram of the principal fasciculi of the spinal cord. (In subacute combined degeneration of spinal cord, the "combined" refers to the fact that the dorsal columns and lateral corticospinal tracts are both affected, in contrast to tabes dorsalis which is selective for the dorsal columns.) | |
Specialty | Neurology |
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