Spinal muscular atrophies
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This article is about a group of rare diseases. For the most common disorder of the group, see Spinal muscular atrophy.
"SMAs" redirects here. For other uses, see SMA (disambiguation) and SMAS (disambiguation).
Spinal muscular atrophies (SMAs) are a genetically and clinically heterogeneous group of rare debilitating disorders characterised by the degeneration of lower motor neurons (neuronal cells situated in the anterior horn of the spinal cord) and subsequent atrophy (wasting) of various muscle groups in the body.[1] While some SMAs lead to early infant death, other diseases of this group permit normal adult life with only mild weakness.
Quick Facts Specialty, Symptoms ...
Spinal muscular atrophies | |
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Location of neurons affected in spinal muscular atrophies | |
Specialty | Neurology |
Symptoms | Loss of motor neurons resulting in muscle wasting |
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