Sitagliptin/metformin
Pharmaceutical drug / From Wikipedia, the free encyclopedia
Sitagliptin/metformin, sold under the brand name Janumet among others, is a fixed-dose combination anti-diabetic medication used to treat type 2 diabetes.[9] It may be used in those whose blood sugar is not controlled with metformin and a sulfonylurea.[9][10] It is taken by mouth.[9]
Combination of | |
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Sitagliptin | Dipeptidyl peptidase-4 inhibitor |
Metformin | Biguanide |
Clinical data | |
Trade names | Janumet, Januet, others |
AHFS/Drugs.com | Professional Drug Facts |
License data | |
Pregnancy category |
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Routes of administration | By mouth |
ATC code | |
Legal status | |
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Identifiers | |
KEGG |
Common side effects include diarrhea, headache, and upper respiratory tract infections.[5] Serious side effects may include lactic acidosis, pancreatitis, low blood sugar, heart failure, joint pain, and allergic reactions.[5] It has not been properly studied in women who are pregnant or breastfeeding.[1] It contains sitagliptin (a dipeptidyl peptidase-4 inhibitor) and metformin (a biguanide).[5]
The combination was approved for medical use in the United States in 2007.[5] In 2021, it was the 154th most commonly prescribed medication in the United States, with more than 3 million prescriptions.[11][12] It is available as a generic medication.[13][14]