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Serum amyloid A1
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Serum amyloid A1 (SAA1) is a protein that in humans is encoded by the SAA1 gene.[5][6][7] SAA1 is a major acute-phase protein mainly produced by hepatocytes in response to infection, tissue injury and malignancy.[8] When released into blood circulation, SAA1 is present as an apolipoprotein associated with high-density lipoprotein (HDL).[9] SAA1 is a major precursor of amyloid A (AA), the deposit of which leads to inflammatory amyloidosis.[10][11]
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