![cover image](https://wikiwandv2-19431.kxcdn.com/_next/image?url=https://upload.wikimedia.org/wikipedia/commons/thumb/3/35/6m5w2.jpg/640px-6m5w2.jpg&w=640&q=50)
Serine hydroxymethyltransferase
InterPro Family / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Serine hydroxymethyltransferase?
Summarize this article for a 10 year old
SHOW ALL QUESTIONS
Serine hydroxymethyltransferase (SHMT) is a pyridoxal phosphate (PLP) (Vitamin B6) dependent enzyme (EC 2.1.2.1) which plays an important role in cellular one-carbon pathways by catalyzing the reversible, simultaneous conversions of L-serine to glycine and tetrahydrofolate (THF) to 5,10-methylenetetrahydrofolate (5,10-CH2-THF).[1] This reaction provides the largest part of the one-carbon units available to the cell.[2]
Quick Facts Identifiers, EC no. ...
Serine hydroxymethyltransferase | |||||||||
---|---|---|---|---|---|---|---|---|---|
![]() Serine hydroxymethyltransferase 1 (cytosolic), homotetramer, Human | |||||||||
Identifiers | |||||||||
EC no. | 2.1.2.1 | ||||||||
CAS no. | 9029-83-8 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
|
Close
![Thumb image](http://upload.wikimedia.org/wikipedia/commons/thumb/e/e9/EcSHMTPyMol.png/640px-EcSHMTPyMol.png)