Selective estrogen receptor modulator
Drugs acting on the estrogen receptor / From Wikipedia, the free encyclopedia
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Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonist/antagonists (ERAAs),[1][2] are a class of drugs that act on the estrogen receptor (ER).[3] A characteristic that distinguishes these substances from pure ER agonists and antagonists (that is, full agonists and silent antagonists) is that their action is different in various tissues, thereby granting the possibility to selectively inhibit or stimulate estrogen-like action in various tissues.
Quick Facts Class identifiers, Synonyms ...
Selective estrogen receptor modulator | |
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Drug class | |
Class identifiers | |
Synonyms | SERM; Estrogen receptor agonist/antagonist; ERAA |
Use | Breast cancer, infertility, osteoporosis, vaginal atrophy, dyspareunia, contraception, male hypogonadism, gynecomastia, breast pain, others |
ATC code | G03XC |
Biological target | Estrogen receptor |
Legal status | |
In Wikidata |
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