Afadin- and alpha-actinin-binding protein is a protein that in humans is encoded by the SSX2IP gene.[5] It has been shown that it functions together with WDR8 in centrosome maturation, ensuring proper spindle length and orientation.[6][7][8][9][10] The SSX2IP-WDR8 complex additionally promotes ciliary vesicle docking during ciliogenesis.[11][12]
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SSX2IP has been initially described as a protein to interact with MLLT4[13] and Actinin, alpha 1.[13] In the context of centrosome maturation and ciliogenesis it has been shown to interact with WDR8.[8][9][11]
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