![cover image](https://wikiwandv2-19431.kxcdn.com/_next/image?url=https://upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Protein_SCRIB_PDB_1uju.png/640px-Protein_SCRIB_PDB_1uju.png&w=640&q=50)
SCRIB
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about SCRIB?
Summarize this article for a 10 year old
SHOW ALL QUESTIONS
SCRIB, also known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene.[5][6] It was originally isolated in Drosophila melanogaster in a pathway (also known as the Scribble complex) with DLGAP5 (Discs large) and LLGL1 (Lethal giant larvae) as a tumor suppressor.[7] In humans, SCRIB is found as a membrane protein and is involved in cell migration, cell polarity, and cell proliferation in epithelial cells.[7][8] There is also strong evidence that SCRIB may play a role in cancer progression because of its strong homology to the Drosophila protein.[7]
Quick Facts Available structures, PDB ...
Close
For the early portable computer, see Scrib.