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Rosterolone
Chemical compound / From Wikipedia, the free encyclopedia
Not to be confused with rotenolone.
Rosterolone (INNTooltip International Nonproprietary Name) (developmental code name SH-434), also known as 17α-propylmesterolone or 1α-methyl-17α-propyl-5α-androstan-17β-ol-3-one, is a steroidal antiandrogen which was first described in 1984 and was developed for topical administration but was never marketed.[1][2] It has shown some efficacy in the treatment of acne, and lacks systemic effects with either topical or systemic administration.[3][1][2] Rosterolone is a derivative of mesterolone, which, in contrast, is an androgen and anabolic steroid.[citation needed]
Quick Facts Clinical data, Other names ...
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Clinical data | |
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Other names | SH-434; 17α-Propylmesterolone; 17β-Hydroxy-1α-methyl-17α-propyl-5α-androstan-3-one |
Routes of administration | Topical |
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ECHA InfoCard | 100.071.904 ![]() |
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Formula | C23H38O2 |
Molar mass | 346.555 g·mol−1 |
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