Radial glial cell
Bipolar-shaped progenitor cells of all neurons in the cerebral cortex and some glia / From Wikipedia, the free encyclopedia
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Radial glial cells, or radial glial progenitor cells (RGPs), are bipolar-shaped progenitor cells that are responsible for producing all of the neurons in the cerebral cortex. RGPs also produce certain lineages of glia, including astrocytes and oligodendrocytes.[2][3][4] Their cell bodies (somata) reside in the embryonic ventricular zone, which lies next to the developing ventricular system.
Radial glial cell | |
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Details | |
Identifiers | |
Latin | gliocytus radialis |
TH | H3.11.08.3.01098 |
Anatomical terms of microanatomy |
During development, newborn neurons use radial glia as scaffolds, traveling along the radial glial fibers in order to reach their final destinations.[3][5][6] Despite the various possible fates of the radial glial population, it has been demonstrated through clonal analysis that most radial glia have restricted, unipotent or multipotent, fates. Radial glia can be found during the neurogenic phase in all vertebrates (studied to date).[7]
The term "radial glia" refers to the morphological characteristics of these cells that were first observed: namely, their radial processes and their similarity to astrocytes, another member of the glial cell family.[8]