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RFX3
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
Transcription factor RFX3 is a protein that in humans is encoded by the RFX3 gene.[5][6]
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This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.[6]