Pseudoexfoliation syndrome
Medical condition / From Wikipedia, the free encyclopedia
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Pseudoexfoliation syndrome, often abbreviated as PEX[1] and sometimes as PES or PXS, is an aging-related systemic disease manifesting itself primarily in the eyes which is characterized by the accumulation of microscopic granular amyloid-like protein fibers.[2] Its cause is unknown, although there is speculation that there may be a genetic basis. It is more prevalent in women than men, and in persons past the age of seventy. Its prevalence in different human populations varies; for example, it is prevalent in Scandinavia.[2] The buildup of protein clumps can block normal drainage of the eye fluid called the aqueous humor and can cause, in turn, a buildup of pressure leading to glaucoma and loss of vision[3] (pseudoexfoliation glaucoma, exfoliation glaucoma). As worldwide populations become older because of shifts in demography, PEX may become a matter of greater concern.[4]
Pseudoexfoliation syndrome | |
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Other names | pseudoexfoliation of the lens, exfoliation syndrome |
Specialty | Ophthalmology |