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Protein that is cleaved from preproglucagon From Wikipedia, the free encyclopedia
Proglucagon is a protein that is cleaved from preproglucagon. Preproglucagon in humans is encoded by the GCG gene.[5][6]
Proglucagon is a precursor of glucagon, and several other components. It is generated in the alpha cells of the pancreas and in the intestinal L cells in the distal ileum and colon. It is also cleaved into the following components in different organs:
Proglucagon itself is a protein with three repeats of slightly different secretin family hormones to be cleaved to form mature hormones.[7]
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