Pregnanolone
Chemical compound / From Wikipedia, the free encyclopedia
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Not to be confused with Pregnenolone.
This article is about the 3α,5β-reduced metabolite of progesterone. For other pregnanolone isomers of progesterone, see Pregnanolone (disambiguation).
Pregnanolone, also known as eltanolone, is an endogenous inhibitory neurosteroid which is produced in the body from progesterone.[4] It is closely related to allopregnanolone, which has similar properties.[4]
Quick Facts Names, Identifiers ...
Names | |
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IUPAC name
3α-Hydroxy-5β-pregnan-20-one | |
Systematic IUPAC name
1-[(1S,3aS,3bR,5aR,7R,9aS,9bS,11aS)-7-Hydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]ethan-1-one | |
Other names
Eltanolone; 5β-Pregnan-3α-ol-20-one; 3α,5β-Tetrahydroprogesterone; 3α,5β-THP; 3α-Hydroxy-5β-tetrahydroprogesterone | |
Identifiers | |
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3D model (JSmol) |
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.162.192 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C21H34O2 | |
Molar mass | 318.501 g·mol−1 |
Pharmacology | |
Intravenous injection[1] | |
Pharmacokinetics: | |
0.9–3.5 hours[1][2][3] | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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